Research stack

SS-31 Mitochondrial Cardiolipin Protocol

SS-31 (elamipretide) protocol for mitochondrial cardiolipin binding and ROS reduction research.

Component peptides

A cationic, mitochondria-targeting tetrapeptide that concentrates at the inner mitochondrial membrane and binds cardiolipin. Investigational; developed for mitochondrial dysfunction — most advanced clinically in Barth syndrome.

Goal

SS-31 protocol for mitochondrial cardiolipin binding and ROS reduction research.

Peptides

SS-31

Why it works

SS-31 selectively binds cardiolipin on the inner mitochondrial membrane, stabilising respiratory-chain supercomplex assembly and reducing electron leak.

How to use

SS-31 — 40 mg once daily subcutaneous.

Last updated: 2026-09-15

Component peptides	SS-31
Duration reported	12 weeks
Cycle pattern	12 weeks continuous
Difficulty	intermediate
Regulatory status	Research use only. None of these compounds is FDA-approved for combined use described.

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